TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos It is found in the

It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I

It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death

the complex is then transported across the cell to be secreted at the apical surface

TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos It is found in theThis gene encodes a member of the transcription elongation factor A (SII) like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.