EGFR Polyclonal Antibody, 50ul[BT-AP02874] Bottles Two alternatively spliced transcript variants

Two alternatively spliced transcript variants that encode different proteins have been described for this gene

and is necessary for removal of the mismatched DNA

Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea

Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK)

EGFR Polyclonal Antibody, 50ul[BT-AP02874] Bottles Two alternatively spliced transcript variantsEpidermal growth factor receptor encoded by EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. Epidermal growth factor receptor is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of tepidermal growth factor receptor to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.