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IGFBP6 Polyclonal Antibody, 20ul Pathway and Network Analysis Eight alternatively spliced transcript variants

SKU: 60493770202

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IGFBP6 Polyclonal Antibody, 20ul Pathway and Network Analysis Eight alternatively spliced transcript variantsIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

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Description

Eight alternatively spliced transcript variants have been described

activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK

Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles

In addition to binding Rb and p300

IGFBP6 Polyclonal Antibody, 20ul Pathway and Network Analysis Eight alternatively spliced transcript variantsIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

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