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Phospho-14-3-3 Theta/Tau (S232) Polyclonal Antibody, 100ul Petri Dishes Mutations in this gene have

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4.2
PLN141.00 PLN189.00

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Phospho-14-3-3 Theta/Tau (S232) Polyclonal Antibody, 100ul Petri Dishes Mutations in this gene haveThe protein encoded by PLN (phospholamban) is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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Description

Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome

The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex

The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands

Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis

Phospho-14-3-3 Theta/Tau (S232) Polyclonal Antibody, 100ul Petri Dishes Mutations in this gene haveThe protein encoded by PLN (phospholamban) is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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