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HER2 Monoclonal Antibody(11H9), 50ul Biomatrix BARD1 encodes a protein which

SKU: 60810458498

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HER2 Monoclonal Antibody(11H9), 50ul Biomatrix BARD1 encodes a protein whichThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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Description

BARD1 encodes a protein which interacts with the N-terminal region of BRCA1

and breast cancer cell proliferation

The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin

Binding to DNA may be mediated by p70

HER2 Monoclonal Antibody(11H9), 50ul Biomatrix BARD1 encodes a protein whichThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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