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TIG1 Polyclonal Antibody, 50ul[BT-AP14966] Buffers & Solutions |Component of the 9-1-1 cell-cycle

SKU: 61184785092

4.0
PLN162.00 PLN190.00

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TIG1 Polyclonal Antibody, 50ul[BT-AP14966] Buffers & Solutions |Component of the 9-1-1 cell-cycleThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.

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Description

|Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair

There is no additional adjustment needed

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily

The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway

TIG1 Polyclonal Antibody, 50ul[BT-AP14966] Buffers & Solutions |Component of the 9-1-1 cell-cycleThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.

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