Arp3 Polyclonal Antibody, 100ul Immune Cell Analysis The protein encoded by MRC1

The protein encoded by MRC1 is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages

Contains 6 IQ domains

Mutations in this gene have been associated with individuals affected by severe intellectual disability| early-onset epilepsy| microcephaly| congenital cataracts| growth retardation| and spasticity (PMID: 25439727)

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Arp3 Polyclonal Antibody, 100ul Immune Cell Analysis The protein encoded by MRC1The specific function of ACTR3 has not yet been determined; however, the protein (ARP3 actin related protein 3 homolog) it encodes is known to be a major constituent of the ARP2 3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for ACTR3.