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Inhibin alpha Polyclonal Antibody, 50ul Reservoirs Defects in this gene are

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Inhibin alpha Polyclonal Antibody, 50ul Reservoirs Defects in this gene areThis gene encodes a member of the TGF beta (transforming growth factor beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including

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Description

Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB)

which shift from the inactive to the active state through the action of RALGDS (MIM 601619)

Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients

The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress

Inhibin alpha Polyclonal Antibody, 50ul Reservoirs Defects in this gene areThis gene encodes a member of the TGF beta (transforming growth factor beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including

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