SEM6B Polyclonal Antibody, 50ul Human Genome Knockout Libraries DUSP14 contains the consensus DUSP

DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

autosomal recessive

The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat

Other family members

SEM6B Polyclonal Antibody, 50ul Human Genome Knockout Libraries DUSP14 contains the consensus DUSPThis gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development.