TLE2 Polyclonal Antibody, 100ul Pathway and Network Analysis Knockout studies in mice suggested
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TLE2 Polyclonal Antibody, 100ul Pathway and Network Analysis Knockout studies in mice suggestedTransducin like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD repeats implicated in protein protein interaction. TLEs are transcriptional co repressors that bind to many transcription factors such as LEF1, Runx1, Oct 1, hepatocyte nuclear factor 3 as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as
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