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and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains

The protein is localized to the cytoplasm

This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing

Gab 2(Phospho Tyr452) Polyclonal Antibody, 20ul Plates & Dishes Unleash the potential of yourThis gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in