PP4R1 Polyclonal Antibody, 100ul Cryopreservation Defects in this gene are

Defects in this gene are associated with HDL deficiencies

consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55

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The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A

PP4R1 Polyclonal Antibody, 100ul Cryopreservation Defects in this gene areThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.