AK5 Polyclonal Antibody, 50ul Peptide Modification MAPT gene mutations have been

MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy

Cys-62 seems to be the major site of palmitoylation

An important paralog of this gene is SLC30A4

where it causes a nonconservative amino acid substitution

AK5 Polyclonal Antibody, 50ul Peptide Modification MAPT gene mutations have beenAK5 encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member (adenylate kinase 5) is related to the UMP CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been