LAX1 Polyclonal Antibody, 50ul Multiplex Immunoassays MRE11A encodes a nuclear protein

MRE11A encodes a nuclear protein involved in homologous recombination

This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes

beta 2 has a more restricted tissue distribution

Mutations in this gene may be associated with susceptibility to coronary artery disease

LAX1 Polyclonal Antibody, 50ul Multiplex Immunoassays MRE11A encodes a nuclear proteinNegatively regulates TCR (T cell antigen receptor) mediated signaling in T cells and BCR (B cell antigen receptor) mediated signaling in B cells.,induction: Up regulated in T cells following TCR engagement.,PTM: Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit: When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity: Expressed in