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Rent1 Polyclonal Antibody, 50ul Serum The product of this gene

SKU: 6526809343

4.1
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Rent1 Polyclonal Antibody, 50ul Serum The product of this geneUPF1 (UPF1, RNA helicase and ATPase) encodes a protein that is part of a post splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense mediated mRNA decay (NMD). When translation ends upstream from the last exon exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located

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Description

The product of this gene belongs to the ficolin family of proteins

It is composed of three C2H2-type zinc-fingers

which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis

Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance

Rent1 Polyclonal Antibody, 50ul Serum The product of this geneUPF1 (UPF1, RNA helicase and ATPase) encodes a protein that is part of a post splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense mediated mRNA decay (NMD). When translation ends upstream from the last exon exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located

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