Hrs(Phospho Tyr216) Polyclonal Antibody, 20ul Biochemical Reagents Cyclin B1 encoded by CCNB1

Cyclin B1 encoded by CCNB1 is a regulatory protein involved in mitosis

Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons

This gene functions as a tumor suppressor gene in a number of common cancers

Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy

Hrs(Phospho Tyr216) Polyclonal Antibody, 20ul Biochemical Reagents Cyclin B1 encoded by CCNB1The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.