Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression This protein may function in

This protein may function in vesicle trafficking| membrane fusion| protein complex assembly and cell motility

This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse

This gene encodes a member of the Rho family of small GTPases

Mutations inCSF1R have been associated with a predisposition to myeloid malignancy

Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression This protein may function inMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.