Phospho-Btk (Y223) Polyclonal Antibody, 50ul NGS Oligos Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases

It specifically binds to chemokine receptor CCR7

which encodes TFIIA-alpha/beta-like factor

Phospho-Btk (Y223) Polyclonal Antibody, 50ul NGS Oligos Gene Ontology (GO) annotations relatedBruton tyrosine kinase encoded by BTK plays a crucial role in B cell development. Mutations in BTK cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.