PSP Polyclonal Antibody, 100ul Immuno Plates Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression

Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression

The DNA-associated protein encoded by paired related homeobox 1 is a member of the paired family of homeobox proteins localized to the nucleus

The gene is located ~4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin

This gene is a member of the BTN2 subfamily of genes

PSP Polyclonal Antibody, 100ul Immuno Plates Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repressionPSPN encodes a secreted ligand of the GDNF (glial cell line derived neurotrophic factor) subfamily and TGF beta (transforming growth factor beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Persephin signals through the RET receptor tyrosine kinase and a GPI linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system