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Tuberin Polyclonal Antibody, 20ul[BT-AP09287] Microbial Genome Editing and with aortic and arterial
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Tuberin Polyclonal Antibody, 20ul[BT-AP09287] Microbial Genome Editing and with aortic and arterialMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
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