RGF1A Polyclonal Antibody, 20ul Centrifuges This gene represents one of

This gene represents one of a cluster of several similar genes located on the q arm of chromosome X

The encoded protein| which belongs to the groucho/TLE family of proteins| can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes

The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

RGF1A Polyclonal Antibody, 20ul Centrifuges This gene represents one ofGuanine nucleotide exchange factor (GEF) for KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.,Contains 1 N terminal Ras GEF domain.,Contains 1 Ras GEF domain.,tissue specificity: Detected in brain and spinal cord. Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies.,