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Stat3(Phospho-Tyr705) Rabbit Polyclonal Antibody, 20ul ssDNA Synthesis Multiple distinct alleles of this

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Stat3(Phospho-Tyr705) Rabbit Polyclonal Antibody, 20ul ssDNA Synthesis Multiple distinct alleles of thisThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.

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Description

Multiple distinct alleles of this locus including the parotid isoelectric-focusing variant slow (PIF-s)| the parotid acidic protein (Pa)| and the double band slow (Db-s) isoforms have been characterized

Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes

The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes

It has virtually no activity for ethanol oxidation| but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione| a spontaneous adduct between formaldehyde and glutathione

Stat3(Phospho-Tyr705) Rabbit Polyclonal Antibody, 20ul ssDNA Synthesis Multiple distinct alleles of thisThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.

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