Sp1 Polyclonal Antibody, 100ul[BT-AP08473] Culture Media The encoded protein contains an

The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and| a C-terminal HECT ubiquitin ligase catalytic domain

including Alzheimer's disease

The protein localizes to the nucleus and the cytoplasm

Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process

Sp1 Polyclonal Antibody, 100ul[BT-AP08473] Culture Media The encoded protein contains anThe protein encoded by SP1 (Sp1 transcription factor) is a zinc finger transcription factor that binds to GC rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly