PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser A mutation in this gene

A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency

TCF4 encodes transcription factor 4

while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes

Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene

PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser A mutation in this geneProprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate