LRRK2 Polyclonal Antibody, 50ul Miscellaneous Keratin 18

Keratin 18

This receptor associates with guanine-nucleotide-binding (G) proteins

sequences which confer targeted degradation to those proteins which contain them

Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)

LRRK2 Polyclonal Antibody, 50ul Miscellaneous Keratin 18This gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.