ALPP/ALPPL2 Polyclonal Antibody, 100ul Pipette Controller Most of the proprotein is

Most of the proprotein is cleaved to make the mature peptide

|disease:Defects in ACAN are the cause of spondyloepiphyseal dysplasia type Kimberley (SEDK)

This gene is a susceptibility locus for childhood absence epilepsy

Alternative splicing results in a multitude of transcript variants

ALPP/ALPPL2 Polyclonal Antibody, 100ul Pipette Controller Most of the proprotein isAlkaline phosphatase, placental type encoded by ALPP is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and