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p27(Phospho Ser10) Polyclonal Antibody, 50ul sgRNA Oligos Catalytic activity of this enzyme

SKU: 70007417477

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p27(Phospho Ser10) Polyclonal Antibody, 50ul sgRNA Oligos Catalytic activity of this enzymeThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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Description

Catalytic activity of this enzyme promotes its nuclear localization

colon and leukocytes

The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase

The protein encoded by this gene is a component of the exocyst complex| a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane

p27(Phospho Ser10) Polyclonal Antibody, 50ul sgRNA Oligos Catalytic activity of this enzymeThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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