EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 20ul Vacuum Filter Alternative splicing of this gene

Alternative splicing of this gene results in two transcript variants encoding different isoforms

Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis

It is the receptor for follicle stimulating hormone and functions in gonad development

The encoded protein may be involved in signal transduction at cell-cell junctions

EGF Receptor(Phospho-Tyr845) Rabbit Polyclonal Antibody, 20ul Vacuum Filter Alternative splicing of this geneThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.