DGK-Theta Polyclonal Antibody, 100ul Molecular Biologyn Research also suggests that USP13

Research also suggests that USP13 is implicated in the pathogenesis of melanoma through its ability to regulate the ubiquitination status of MITF

Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin

termed CAMEL

and it can promote cell survival in prostate cancer

DGK-Theta Polyclonal Antibody, 100ul Molecular Biologyn Research also suggests that USP13Diacylglycerol kinase theta encoded by DGKQ contains three cysteine rich domains, a proline rich region, and a pleckstrin homology domain with an overlapping Ras associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI cycle during cell signal transduction.