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MTMR5 Rabbit Polyclonal Antibody, 20ul General Lab Use MRPL42 encodes mitochondrial ribosomal protein

SKU: 70796127169

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MTMR5 Rabbit Polyclonal Antibody, 20ul General Lab Use MRPL42 encodes mitochondrial ribosomal proteinThis gene encodes a member of the protein tyrosine phosphatase family. However the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot Marie Tooth disease 4B3. Pseudogenes of this

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Description

MRPL42 encodes mitochondrial ribosomal protein L42 identified as belonging to both the 28S and the 39S subunits

No other protein can be recognized by this antibody from the sequence BLAST results

However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined

while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly

MTMR5 Rabbit Polyclonal Antibody, 20ul General Lab Use MRPL42 encodes mitochondrial ribosomal proteinThis gene encodes a member of the protein tyrosine phosphatase family. However the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot Marie Tooth disease 4B3. Pseudogenes of this

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