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TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters The encoded transmembrane protein binds

SKU: 71044808536

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TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters The encoded transmembrane protein bindsThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.

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Description

The encoded transmembrane protein binds to SEMA3C protein {sema domain

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes

MBP is a useful affinity tag that can increase the expression level and solubility of the resulting tagged protein

A sequence polymorphism has been identified in the 3'UTR of the third exon

TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters The encoded transmembrane protein bindsThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.

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