Human Agouti-signaling Protein, ASIP ELISA Kit , 96T Glassware Sets ERCC excision repair 4
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Human Agouti-signaling Protein, ASIP ELISA Kit , 96T Glassware Sets ERCC excision repair 4Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha MSH initiated signaling and thus blocks production of cAMP, leading to a down regulation of eumelanogenesis (brown black pigment) and thus increasing synthesis of pheomelanin (yellow red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of
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