Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library The encoded protein product is

The encoded protein product is a preproprotein

The gene is expressed in most nonlymphoid human tissues including prostate

The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties| a region within repeats 5-7 having heparin binding and C reactive protein binding properties| and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain

An important paralog of this gene is LONP1

Tuberin Polyclonal Antibody, 100ul[BT-AP09287] Peptide Library The encoded protein product isMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.