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Beclin-1 mouse Monoclonal Antibody(5C5), 50ul Filtration This gene is located within

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SEK185.00 SEK219.00

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Beclin-1 mouse Monoclonal Antibody(5C5), 50ul Filtration This gene is located withinThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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Description

This gene is located within the Smith-Magenis syndrome region on chromosome 17

Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system

subunit:Oligomerizes and associates with TNKS

It binds mutliple lipid-containing molecules| including phosphatidylserine| phosphatidylinositol 4-phosphate (PI4P) and oxysterol| and promotes their exchange between the endoplasmic reticulum and the plasma membrane

Beclin-1 mouse Monoclonal Antibody(5C5), 50ul Filtration This gene is located withinThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

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