Gab 1 Polyclonal Antibody, 100ul[BT-AP03408] Polyclonal Antibodies 653 bases and maps to

653 bases and maps to human chromosome 2q14

This protein is localized to the centrosome

as well as RNA polymerase II protein complexes

The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1

Gab 1 Polyclonal Antibody, 100ul[BT-AP03408] Polyclonal Antibodies 653 bases and maps toThe GRB2 associated binding protein 1 encoded by GAB1 is a member of the IRS1 like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.