KPCD2 Polyclonal Antibody, 100ul Stepper and macular dystrophy syndrome (EEMS)

and macular dystrophy syndrome (EEMS)

Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10)

Unlike the ubiquitous expression of ribosomal protein genes

it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration

KPCD2 Polyclonal Antibody, 100ul Stepper and macular dystrophy syndrome (EEMS)The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding