PAK5 Polyclonal Antibody, 20ul Cell Biology Calpains constitute a family of

Calpains constitute a family of intracellular calcium-dependent cysteine proteases

The encoded protein (cholinergic receptor nicotinic alpha 3 subunit) is a ligand-gated ion channel that likely plays a role in neurotransmission

It is a mediator of mitochondrial damage induced by caspase-8 (CASP8)

Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family

PAK5 Polyclonal Antibody, 20ul Cell Biology Calpains constitute a family ofp21 (RAC1) activated kinase 5 encoded by PAK5 is a member of the PAK family of Ser Thr protein kinases. PAK family members are known to be effectors of Rac Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42 Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in