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Raf-1 Polyclonal Antibody, 20ul[BT-AP13536] Pipette Controller cyclin G2 contains a C-terminal

SKU: 72748008405

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Raf-1 Polyclonal Antibody, 20ul[BT-AP13536] Pipette Controller cyclin G2 contains a C-terminalThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

cyclin G2 contains a C-terminal PEST protein destabilization motif

another basic helix-loop-helix protein that binds to MYC and is required for its function

Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene

forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli

Raf-1 Polyclonal Antibody, 20ul[BT-AP13536] Pipette Controller cyclin G2 contains a C-terminalThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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