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CALRL Polyclonal Antibody, 50ul Cell Function Analysis OGF is a negative regulator

SKU: 72867089573

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CALRL Polyclonal Antibody, 50ul Cell Function Analysis OGF is a negative regulatorReceptor for calcitonin gene related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,Belongs to the G protein coupled receptor 2 family.,subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity: Predominantly expressed in the lung and heart.,

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Description

OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells

and telecanthus (MMCAT) and cone-rod dystrophy in human patients

It has been associated with multiple functions| including axon membrane trafficking| axonal homeostasis| mitophagy| adipose differentiation| and hematopoietic stem cell maintenance

CALRL Polyclonal Antibody, 50ul Cell Function Analysis OGF is a negative regulatorReceptor for calcitonin gene related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,Belongs to the G protein coupled receptor 2 family.,subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity: Predominantly expressed in the lung and heart.,

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