Tryptase-3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The von Hippel-Lindau tumor suppressor

The von Hippel-Lindau tumor suppressor protein binds to elongins B and C

cell cycle progression and developmental events

Multiple alternatively spliced transcript variants have been described

This gene is a candidate gene for Hirschsprung disease

Tryptase-3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The von Hippel-Lindau tumor suppressorTryptases comprise a family of trypsin like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13. 3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which