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CD56 Polyclonal Antibody, 50ul[BT-AP01633] Metabolic enzymes The encoded protein does not

SKU: 73781439933

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CD56 Polyclonal Antibody, 50ul[BT-AP01633] Metabolic enzymes The encoded protein does notCDK5RAP2 (CDK5 regulatory subunit associated protein 2) encodes a regulator of CDK5 (cyclin dependent kinase 5) activity. The protein encoded by CDK5RAP2 is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

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Description

The encoded protein does not have a transmembrane domain

Mutations in this gene are associated with gastrointestinal stromal tumors

Increases p53/TP53-dependent transcription and apoptosis

suggesting that this gene may have a role in the p53-dependent growth regulatory pathway

CD56 Polyclonal Antibody, 50ul[BT-AP01633] Metabolic enzymes The encoded protein does notCDK5RAP2 (CDK5 regulatory subunit associated protein 2) encodes a regulator of CDK5 (cyclin dependent kinase 5) activity. The protein encoded by CDK5RAP2 is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

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