NF-κB p65 Polyclonal Antibody, 50ul Cell Culture Members of this Type 1

Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats

It has a wider tissue distribution than CA VA

This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1

Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen)

NF-κB p65 Polyclonal Antibody, 50ul Cell Culture Members of this Type 1NF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL RELA or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene RELA. Four