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p53 Monoclonal Antibody, 50ul[BT-MCA0977] Long RNA Synthesis RPL27A encodes a ribosomal protein

SKU: 74717357584

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p53 Monoclonal Antibody, 50ul[BT-MCA0977] Long RNA Synthesis RPL27A encodes a ribosomal proteinThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

RPL27A encodes a ribosomal protein that is a component of the 60S subunit

This gene is one of the "framework" loci that is present on all haplotypes

The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways

Gene Ontology (GO) annotations related to this gene include alpha-tubulin binding

p53 Monoclonal Antibody, 50ul[BT-MCA0977] Long RNA Synthesis RPL27A encodes a ribosomal proteinThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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