Beclin-1 mouse Monoclonal Antibody(5C2), 100ul Peripheral Blood Separation Tube q21) that result in fusion

q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma

Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner

If both delta and gamma rearrangements produce functional chains| the cell expresses delta and gamma

Contains 2 SAM (sterile alpha motif) domains

Beclin-1 mouse Monoclonal Antibody(5C2), 100ul Peripheral Blood Separation Tube q21) that result in fusionThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.