53BP1 Polyclonal Antibody, 50ul[BT-AP00040] Centrifugal Filter Among its related pathways are

Among its related pathways are Metabolism and Sphingolipid metabolism

Casein kinase I isoform delta may also be involved in the regulation of apoptosis

such that the alleles were once thought to represent two separate gene

CD5 (CD5 Molecule) is a Protein Coding gene

53BP1 Polyclonal Antibody, 50ul[BT-AP00040] Centrifugal Filter Among its related pathways areThe p53 binding proteins 53BP1 and 53BP2 (Bbp) bind to the central DNA binding domain of wild type p53, but do not bind mutant p53. The central DNA binding domain of p53 is required for site specific DNA binding and is frequently mutated in malignant tumors. Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation. Site specific binding also suggests that 53BP1 and 53BP2 are