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GIT2 Polyclonal Antibody, 100ul Antibody Humanization Phosphorylates and activates MAP2K4 and

SKU: 77233357298

4.4
SEK141.00 SEK191.00

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GIT2 Polyclonal Antibody, 100ul Antibody Humanization Phosphorylates and activates MAP2K4 andGIT2 encodes a member of the GIT protein family, ARF GTPase activating protein GIT2, which interact with G protein coupled receptor kinases and possess ADP ribosylation factor (ARF) GTPase activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins.

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Description

Phosphorylates and activates MAP2K4 and MAP2K6| which in turn activate the JNK and p38 MAP kinases| respectively

This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression

the predicted protein lacks most of the C-terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins

MGST3 encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family

GIT2 Polyclonal Antibody, 100ul Antibody Humanization Phosphorylates and activates MAP2K4 andGIT2 encodes a member of the GIT protein family, ARF GTPase activating protein GIT2, which interact with G protein coupled receptor kinases and possess ADP ribosylation factor (ARF) GTPase activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins.

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