GCSc-Gamma Polyclonal Antibody, 100ul Multiplex Immunoassays Mutations at highly conserved amino

Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies

The mu class of enzymes functions in the detoxification of electrophilic compounds| including carcinogens| therapeutic drugs| environmental toxins and products of oxidative stress| by conjugation with glutathione

This protein localizes to cytoplasmic filaments

NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65| RELB| NFKB1/p105| NFKB1/p50| REL and NFKB2/p52

GCSc-Gamma Polyclonal Antibody, 100ul Multiplex Immunoassays Mutations at highly conserved aminoGlutamate cysteine ligase, also known as gamma glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22 p21. Mutations at GCLC have been associated with hemolytic anemia due to