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p53 Polyclonal Antibody, 50ul[BT-AP06819] Capsule Filter Inhibition of this protein's activity

SKU: 77833981029

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p53 Polyclonal Antibody, 50ul[BT-AP06819] Capsule Filter Inhibition of this protein's activityTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Inhibition of this protein's activity may confer anticancer benefits

Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6

Studies have also characterized the protein as an RNA polymerase II elongation factor

With 50 reactions and 1 reaction per μl

p53 Polyclonal Antibody, 50ul[BT-AP06819] Capsule Filter Inhibition of this protein's activityTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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