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Histone H2A Polyclonal Antibody, 100ul[BT-AP04000] Cell Labeling & Imaging Increases the ability of FGFR1

SKU: 7877746804

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Histone H2A Polyclonal Antibody, 100ul[BT-AP04000] Cell Labeling & Imaging Increases the ability of FGFR1Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.

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Description

Increases the ability of FGFR1 and FGFR4 to bind FGF21

The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily

The encoded protein plays an important role in maintaining stem cell populations| and may be aberrantly expressed in tumor cells

Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML)

Histone H2A Polyclonal Antibody, 100ul[BT-AP04000] Cell Labeling & Imaging Increases the ability of FGFR1Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.

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