AGRIN Polyclonal Antibody, 100ul Miscellaneous AKAP8 encodes a member of

AKAP8 encodes a member of the A-kinase anchor protein family

and the membrane-spanning component

Chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million bases

Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene

AGRIN Polyclonal Antibody, 100ul Miscellaneous AKAP8 encodes a member ofThis gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ) as identified in mouse knock out studies. The encoded protein contains several laminin G Kazal type serine protease inhibitor and epidermal growth factor domains. Additional post translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb girdle muscles